
Southeast Iowa Vacations from $646
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Your Southeast Iowa Vacation
Enjoy the flexibility to travel wherever your wanderlust takes you when you book a Southeast Iowa vacation package. From its rich history to a whole lot more, you can experience it all at your own speed. A carefully planned itinerary is a must for your trip to Southeast Iowa. Burlington, Mount Pleasant and Keokuk are a few of the most well-known cities here. Whether you're traveling for a few days or a few weeks, Expedia are here to help you organize your next dream Southeast Iowa vacation.
The Latest Southeast Iowa vacation packages

Fun City Resort Hotel
Reviewed on Aug 4, 2025

Willard Richards Inn
Reviewed on Jun 22, 2025

The Catfish Bend Inn & Spa
Reviewed on Jul 30, 2025

Cobblestone Inn & Suites - Fort Madison
Reviewed on Jul 30, 2025

Johnstone Mansion
Reviewed on Jul 19, 2025
Discover the most popular places to visit in Southeast Iowa

Snake Alley
Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.
Historic Nauvoo
Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.
FunCity
Enjoy an outing to FunCity during your stay in Burlington. Visit the area's casinos, or simply enjoy its bars.
Southeast Iowa Hotel Deals

The Catfish Bend Inn & Spa
Reviewed on Aug 4, 2025

Fun City Resort Hotel
Reviewed on Aug 4, 2025

Cobblestone Inn & Suites - Fort Madison
Reviewed on Aug 2, 2025