
Southeast Iowa Vacations
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Your Southeast Iowa Vacation
Enjoy the flexibility to travel wherever your wanderlust takes you when you book a Southeast Iowa vacation package. From its rich history to a whole lot more, you can experience it all at your own speed. A carefully planned itinerary is a must for your trip to Southeast Iowa. Burlington, Mount Pleasant and Keokuk are a few of the most well-known cities here. Whether you're traveling for a few days or a few weeks, Expedia are here to help you organize your next dream Southeast Iowa vacation.
Discover the most popular places to visit in Southeast Iowa

Snake Alley
Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.
FunCity
Enjoy an outing to FunCity during your stay in Burlington. Visit the area's casinos, or simply enjoy its bars.
Historic Nauvoo
Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.
Southeast Iowa Hotel Deals

Cobblestone Inn & Suites - Fort Madison
Really nice hotel, especially when it's below zero and snowing.
Reviewed on Dec 24, 2025

Quality Inn & Suites Keokuk North
Decent room. Good breakfast.
Reviewed on Dec 22, 2025

Nauvoo Temple House Hotel
Beds were comfy. Staff was helpful.
Reviewed on Dec 18, 2025
Find the Best Southeast Iowa Vacation Packages
Southeast Iowa Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Des Moines Intl. Airport (DSM) |



















